Solubility:   Partly soluble in water.
Appearance:   Brownish-red powder, with slight oder,taste with a litter bitter.
Pharmacology Action:  1.Prevent skin aging and inhibites UV radiation
2.Enhance capillary strength and vascular function
3.Penetrate the blood-brain barrier to help protection of the brain and nerve tissue from oxidation
4.Alleviate PMS problems,brusing,edema from injury or trauma,varicose veins,leg swelling and retinopathy
Potential anti-disease effects:Grape seed extract may be useful to treat heart diseases such as high blood pressure and high cholesterol.By limiting lipid oxidation, phenolics in grape seeds may reduce risk of heart disease, such as by inhibiting platelet aggregation and reducing inflammation.A polyphenol contained in grape seeds is resveratrol which may interfere with cancer cell growth and proliferation, as well as induce apoptosis, among a variety of potential chemopreventive effects.Grape seed components may also be active against HIV by inhibiting virus expression and replication. 
Grape seed extract may have other possible anti-disease properties, such as:1.wound healing -- grape seed proanthocyanidins induced vascular endothelial growth factor and accelerated healing of injured skin in mice.2.tooth decay -- seed phenolics may inhibit oral sugar metabolism and retard growth of certain bacteria causing dental caries.3.osteoporosis -- grape seed extracts enhanced bone density and strength in experimental animals.4.skin cancer -- grape seed proanthocyanidins decreased tumor numbers and reduced the malignancy of papillomas.5.ultraviolet damage to skin -- dietary proanthocyanidins may protect against carcinogenesis and provide supplementation for sunscreen protection.